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Douglas Hanahan Douglas Hanahan Douglas Hanahan Douglas Hanahan
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Douglas Hanahan est un biologiste américain né en 1951. Il est professeur à l'École polytechnique fédérale de Lausanne et directeur de l'Institut suisse de recherche expérimentale sur le cancer (ISREC). Avec Robert Weinberg, il est auteur des articles scientifiques « The hallmarks of cancer » et « Hallmarks of cancer: the next generation ». Douglas „Doug“ Hanahan (* 1951 in Seattle) ist ein US-amerikanischer Biochemiker und Krebsforscher. Er ist Professor an der École polytechnique fédérale de Lausanne und Leiter des Schweizerischen Instituts für Experimentelle Krebsforschung (ISREC). Gemeinsam mit Robert Allan Weinberg verfasste Hanahan zwei vielzitierte Arbeiten, die die wichtigsten biologischen Eigenschaften von Krebs zusammenfassten: The Hallmarks of Cancer und Hallmarks of Cancer: The Next Generation.Eine weitere Aktualisierung veröffentlichte Hanahan 2022 unter dem Titel Hallmarks of Cancer: New Dimensions Douglas Hanahan (born 1951) is an American biologist, professor and director emeritus of the Swiss Institute for Experimental Cancer Research at EPFL (École polytechnique Fédérale de Lausanne) in Lausanne, Switzerland. He is currently member of the Lausanne branch of the Ludwig Institute. Douglas Hanahan (nascido em 1951) é um biólogo norte-Americano, professor e diretor do Centro Suíco de Oncologia do Instituto Federal Suíço de Tecnologia em Lausanne (EPFL). Em 1983, ele desenvolveu o Super Ótimo Caldo, uma microbiológica de crescimento médio. Ele também melhorou os protocolos utilizados para a transformação de Escherichia coli. Em 2014, ele recebeu o Lifetime Achievement na Pesquisa do Câncer Prêmio da Associação Americana para Pesquisa do Câncer.
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Douglas Hanahan in 2017 at EPFL
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"DH5-Alpha Cell" named after him "The Hallmarks of Cancer"
dbo:abstract
Douglas Hanahan est un biologiste américain né en 1951. Il est professeur à l'École polytechnique fédérale de Lausanne et directeur de l'Institut suisse de recherche expérimentale sur le cancer (ISREC). Avec Robert Weinberg, il est auteur des articles scientifiques « The hallmarks of cancer » et « Hallmarks of cancer: the next generation ». Douglas Hanahan (nascido em 1951) é um biólogo norte-Americano, professor e diretor do Centro Suíco de Oncologia do Instituto Federal Suíço de Tecnologia em Lausanne (EPFL). Em 1983, ele desenvolveu o Super Ótimo Caldo, uma microbiológica de crescimento médio. Ele também melhorou os protocolos utilizados para a transformação de Escherichia coli. Com Robert Weinberg, ele escreveu um artigo seminal Os signos de Câncer, publicado em janeiro de 2000, e que, em Março de 2011, é o mais frequentemente citado artigo de revisão pelos pares diário da Célula. Em 2011, eles publicaram uma revisão atualizada do artigo intitulado "Características do câncer: a próxima geração". Em 2014, ele recebeu o Lifetime Achievement na Pesquisa do Câncer Prêmio da Associação Americana para Pesquisa do Câncer. Douglas Hanahan (born 1951) is an American biologist, professor and director emeritus of the Swiss Institute for Experimental Cancer Research at EPFL (École polytechnique Fédérale de Lausanne) in Lausanne, Switzerland. He is currently member of the Lausanne branch of the Ludwig Institute. He received his PhD from Harvard University in 1983. In 1983, he developed Super Optimal Broth, a microbiological growth medium. He also improved the protocols used for plasmid transformation of Escherichia coli.In the 1980s, he developed one of the first transgenic mouse models of cancer.With Robert Weinberg, he wrote a seminal paper The Hallmarks of Cancer, published in January 2000, and which in March 2011 is the most often cited article from the peer reviewed journal Cell. In 2011, they published an updated review article entitled "Hallmarks of cancer: the next generation". In 2022, Professor Hanahan published another updated review article entitled "Hallmarks of Cancer: New Dimensions" on the peer reviewed journal Cancer Discovery. Douglas „Doug“ Hanahan (* 1951 in Seattle) ist ein US-amerikanischer Biochemiker und Krebsforscher. Er ist Professor an der École polytechnique fédérale de Lausanne und Leiter des Schweizerischen Instituts für Experimentelle Krebsforschung (ISREC). Hanahan erwarb 1976 am Massachusetts Institute of Technology einen Bachelor in Physik. Anschließend schrieb er sich an der Harvard University für Biochemie und Molekularbiologie ein, verbrachte aber die meiste Zeit im Cold Spring Harbor Laboratory (CSHL), einer der wenigen Einrichtungen, die damals mit rekombinanter DNA bei Bakterien arbeiten durfte. Hier erwarb er 1983 einen PhD, verbesserte die Methoden zur Einschleusung rekombinanter DNA bei Bakterien erheblich und entwickelte das SOB-Medium, ein Nährmedium für Bakterien. Hanahan blieb auch nach dem Abschluss als Forscher am CSHL. 1988 erhielt er eine Professur an der University of California, San Francisco, die er bis 2010 innehatte. Am Schweizerischen Institut für Experimentelle Krebsforschung (ISREC) arbeitet er mit genetisch veränderten menschlichen Tumorzellen, deren Entwicklung zu invasiven und metastasierenden Krebserkrankungen er am Mausmodell untersucht. Schwerpunkte seiner Arbeit sind einerseits die Bedeutung des Stroma und der Tumormikroumgebung, andererseits die Entwicklung präklinischer Tests um neue Krebstherapien zu entwickeln. Gemeinsam mit Robert Allan Weinberg verfasste Hanahan zwei vielzitierte Arbeiten, die die wichtigsten biologischen Eigenschaften von Krebs zusammenfassten: The Hallmarks of Cancer und Hallmarks of Cancer: The Next Generation.Eine weitere Aktualisierung veröffentlichte Hanahan 2022 unter dem Titel Hallmarks of Cancer: New Dimensions 2007 wurde Hanahan zum Mitglied der American Academy of Arts and Sciences gewählt, 2009 der National Academy of Sciences und 2010 der European Molecular Biology Organization. 2010 erhielt er ein Ehrendoktorat der University of Dundee und 2014 den AACR Award for Lifetime Achievement in Cancer Research der American Association for Cancer Research.
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