Roscoe Owen Brady (October 11, 1923 – 13 June 2016) was an American biochemist. He attended the Pennsylvania State University and obtained his M.D. degree from Harvard Medical School in 1947. He interned at the Hospital of the University of Pennsylvania. From 1948 to 1952 he was a post-doctoral fellow in the Department of Physiological Chemistry at the University of Pennsylvania School of Medicine and fellow in clinical medicine in the Department of Medicine. In collaboration with Samuel Gurin at the University of Pennsylvania, Brady discovered the enzyme system for the biosynthesis of long chain fatty acids, and later discovered the role of malonate coenzyme A in this process. After two and one-half years on active duty in the U.S. Naval Medical Corps, he joined the National Institutes of