Raffaella Buonsanti (born 1981 in Matera, Italy) is an Italian chemist and material scientist. Her research is at the interface between materials chemistry and catalysis as she focuses on the synthesis of nanocrystals to drive various energy-related reactions, such as CO2 reduction. She is currently a tenure-track assistant professor at École Polytechnique Fédérale de Lausanne (EPFL) and director of the Laboratory of Nanochemistry for Energy located at EPFL's Valais campus.