Zechariah Symmes (5 April 1599, in Canterbury – 4 February 1671, in Charlestown, Massachusetts) was an English Puritan clergyman who emigrated to the Massachusetts Bay Colony in New England and became pastor of the First Church in Charlestown, an office he held continuously from 1634 to his death in 1671. Although not one of the original Charlestown founders of 1629, on arrival in 1634 he swiftly found his place among them in the church they had convened two years previously. One of the many emigrant ministers who emerged from Emmanuel College, Cambridge, he was a close fellow-worker among the leading lights of the "Bible Commonwealth".