About: Sérgio Henrique Ferreira

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Sérgio Henrique Ferreira (October 4, 1934 – July 17, 2016) was a Brazilian physician and pharmacologist noted for the discovery of the bradykinin potentiating factor, which led to new and widely used anti-hypertension drugs — the ACE inhibitors.

Attributes	Values
rdf:type	Thing foaf:Person person dul:NaturalPerson Eukaryote Person Human Animal yago:WikicatBrazilianPeople yago:WikicatBrazilianPharmacologists yago:WikicatBrazilianPhysicians yago:WikicatBrazilianScientists animal eukaryote scientist species schema:Person yago:WikicatLivingPeople Scientist yago:Adult109605289 yago:CausalAgent100007347 yago:Doctor110020890 yago:HealthProfessional110165109 yago:LivingThing100004258 yago:MedicalPractitioner110305802 yago:Object100002684 yago:Organism100004475 yago:Person100007846 yago:Pharmacist110421470 yago:Pharmacologist110421753 yago:PhysicalEntity100001930 yago:Professional110480253 yago:YagoLegalActor yago:YagoLegalActorGeo yago:Scientist110560637 yago:Whole100003553 yago:WikicatPeopleFromSãoPaulo(state) yago:WikicatPharmacologists
rdfs:label	سيرجيو هنريكي فيريرا (ar) Sérgio Henrique Ferreira (de) Sérgio Henrique Ferreira (pl) Sérgio Henrique Ferreira (pt) Sérgio Henrique Ferreira (en)
rdfs:comment	سيرجيو هنريكي فيريرا (بالبرتغالية: Sérgio Henrique Ferreira‏) هو ‏ برازيلي، ولد في 10 أبريل 1934 في فرانكا في البرازيل، وتوفي في 17 يوليو 2016 في ريبيراو بريتو في البرازيل. (ar) Sérgio Henrique Ferreira (October 4, 1934 – July 17, 2016) was a Brazilian physician and pharmacologist noted for the discovery of the bradykinin potentiating factor, which led to new and widely used anti-hypertension drugs — the ACE inhibitors. (en) Sérgio Henrique Ferreira (* 4. Oktober 1934 in Franca, Bundesstaat São Paulo, Brasilien; † 17. Juli 2016 in Ribeirão Preto, Bundesstaat São Paulo) war ein brasilianischer Pharmakologe und Arzt. Ferreira studierte an der Universität São Paulo (USP) an der Medizinischen Fakultät in Ribeirão Preto. Er forschte dort bei (dem Entdecker von Bradykinin) in der Pharmakologie. Dort entdeckte er Peptide im Gift der Jararaca-Lanzenotter (Bothrops jararaca), die den Effekt von Bradykinin erheblich verstärkten (Bradykinin Potentiating Factor, BPF). 1968 konnte er in Zusammenarbeit mit Lewis Joel Greene vom Brookhaven National Laboratory die BPF-Peptide genauer charakterisieren und deren Struktur aufklären. Es unterdrückt Angiotensin I Konversion (über das Angiotensin Converting Enzyme, ACE). Das führt (de) Sérgio Henrique Ferreira (ur. 4 października 1934 we Franca, São Paulo, zm. 17 lipca 2016 w Ribeirão Preto, São Paulo) – brazylijski naukowiec, lekarz, farmakolog. Pionier badań nad mechanizmem działania bradykininy. Odkrył bradykinin potentiating factor (BPF), czynnik nasilający działanie bradykininy. Jego badania stały się podstawą do wynalezienia leków hipotensyjnych z grupy inhibitorów konwertazy angiotensyny. Podczas swojego stażu w Londynie na przełomie lat 60. i 70. współpracował z Johnem Vane'em w jego badaniach nad prostaglandynami. (pl) Sérgio Henrique Ferreira (Franca, 4 de outubro de 1934 - Ribeirão Preto, 17 de julho de 2016) foi um médico e farmacologista brasileiro, notável pela sua descoberta o fator de potenciação da bradicinina, um peptídeo extraído do veneno da Bothrops jararaca (Jararaca-da-mata), o que possibilitou o desenvolvimento do captopril, um medicamento usado no tratamento da hipertensão arterial. Foi professor da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo. Morreu em 17 de julho de 2016, aos 81 anos, de insuficiência respiratória. (pt)
birth place	Brazil Franca São Paulo (state)
death place	Brazil Ribeirão Preto São Paulo (state)
death place	Ribeirão Preto, São Paulo, Brazil (en)
death date	2016-07-17 (xsd:date)
birth place	Brazil Franca São Paulo (state)
birth date	1934-10-04 (xsd:date)
dcterms:subject	Members of the Brazilian Academy of Sciences Brazilian pharmacologists 1934 births Foreign associates of the National Academy of Sciences TWAS laureates 2016 deaths People from Franca University of São Paulo alumni Recipients of the Great Cross of the National Order of Scientific Merit (Brazil)
Wikipage page ID	1459354 (xsd:integer)
Wikipage revision ID	1118374797 (xsd:integer)
Link from a Wikipage to another Wikipage	Prostaglandins Bradykinin potentiating factor Bradykinin Brazil Members of the Brazilian Academy of Sciences Hypertension John Vane Peptide Pharmacology Ribeirão Preto Cytokine United States University of São Paulo Interleukin Premio México de Ciencia y Tecnología Brazilian pharmacologists Bothrops Bothrops jararaca TWAS Prize Lewis Joel Greene London Bristol-Myers Squibb 1934 births Foreign associates of the National Academy of Sciences Brookhaven National Laboratory Doctor of Medicine ACE inhibitors Analgesic TWAS laureates

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