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Pyronaridine is an antimalarial drug. It was first made in 1970 and has been in clinical use in China since the 1980s. In a small (n=88) malaria study in Camaroon, pyronaridine had a 100% cure rate, compared with 60% for chloroquine. It is one of the components of the artemisinin combination therapy pyronaridine/artesunate (Pyramax).

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rdf:type
rdfs:label
  • Pyronaridine (en)
  • بيرونيردين (ar)
  • Pyronarydyna (pl)
  • 咯萘啶 (zh)
rdfs:comment
  • بيرونيردين هو دواءٌ مضادٌ للملاريا. صُنع للمرة الأولى في عام 1970 وكان قيد الاستخدام السريري في الصين منذ ثمانينيات القرن العشرين. يعتبر البيرونيردين واحدًا من مكونات العلاج المركب بالأرتيميسينين أرتيسونات/بيرونيردين. أُجريت دراساتٌ على البيرونيردين لاستخدامه المُحتمل مضادًا للسرطان. (ar)
  • Pyronarydyna (łac. pyronaridinum) – wielofunkcyjny organiczny związek chemiczny, pochodna , stosowana w leczeniu malarii w połączeniu z artezunatem. (pl)
  • 咯萘啶是一种抗疟疾药物。它于1970年首次制造，自20世纪80年代以来一直在中国临床使用。 咯萘啶是苯并萘啶的衍生物，为中国研制的一种抗疟药。对红内期疟原虫有杀灭作用，对耐氯喹的恶性虐也有效。 (zh)
  • Pyronaridine is an antimalarial drug. It was first made in 1970 and has been in clinical use in China since the 1980s. In a small (n=88) malaria study in Camaroon, pyronaridine had a 100% cure rate, compared with 60% for chloroquine. It is one of the components of the artemisinin combination therapy pyronaridine/artesunate (Pyramax). (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Pyronaridine.svg
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Wikipage page ID
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alt
  • A chemical diagram of a Pyronaridine molecule (en)
ATC prefix
  • none (en)
c
CAS number
ChEMBL
ChemSpiderID
Cl
H
IUPAC name
legal status
n
O
PubChem
routes of administration
  • Oral, intramuscular injection, intravenous therapy (en)
SMILES
  • Clc1ccc6cnc2cccnc2c6Nc5ccccc5 (en)
StdInChI
StdInChIKey
  • DJUFPMUQJKWIJB-UHFFFAOYSA-N (en)
synonyms
  • Pyronaridine tetraphosphate (en)
UNII
  • TD3P7Q3SG6 (en)
Verifiedfields
  • changed (en)
verifiedrevid
Watchedfields
  • changed (en)
has abstract
  • بيرونيردين هو دواءٌ مضادٌ للملاريا. صُنع للمرة الأولى في عام 1970 وكان قيد الاستخدام السريري في الصين منذ ثمانينيات القرن العشرين. يعتبر البيرونيردين واحدًا من مكونات العلاج المركب بالأرتيميسينين أرتيسونات/بيرونيردين. أُجريت دراساتٌ على البيرونيردين لاستخدامه المُحتمل مضادًا للسرطان. (ar)
  • Pyronaridine is an antimalarial drug. It was first made in 1970 and has been in clinical use in China since the 1980s. In a small (n=88) malaria study in Camaroon, pyronaridine had a 100% cure rate, compared with 60% for chloroquine. It is one of the components of the artemisinin combination therapy pyronaridine/artesunate (Pyramax). It has also been studied as a potential anticancer drug, and treatment for Ebola. The combination of pyronaridine and artesunate has been evaluated to have a synergistic effect of stronger antiviral effect and less toxicity. The combination of pyronaridine and artesunate is being studied as a possible treatment for moderate to severe SARS-COV-2. (en)
  • Pyronarydyna (łac. pyronaridinum) – wielofunkcyjny organiczny związek chemiczny, pochodna , stosowana w leczeniu malarii w połączeniu z artezunatem. (pl)
  • 咯萘啶是一种抗疟疾药物。它于1970年首次制造，自20世纪80年代以来一直在中国临床使用。 咯萘啶是苯并萘啶的衍生物，为中国研制的一种抗疟药。对红内期疟原虫有杀灭作用，对耐氯喹的恶性虐也有效。 (zh)
gold:hypernym
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page length (characters) of wiki page
CAS number
  • 74847-35-1
ChEMBL
  • 35228
FDA UNII code
  • TD3P7Q3SG6
PubChem
  • 5485198
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