About: Pyrin domain     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Unit108189659, within Data Space : dbpedia.org associated with source document(s)
QRcode icon
http://dbpedia.org/describe/?url=http%3A%2F%2Fdbpedia.org%2Fresource%2FPyrin_domain

A pyrin domain (PYD, also known as PAAD/DAPIN) is a protein domain and a subclass of protein motif known as the death fold, the 4th and most recently discovered member of the death domain superfamily (DDF). It was originally discovered in the pyrin protein, or marenostrin, encoded by MEFV. The mutation of the MEFV gene is the cause of the disease known as Familial Mediterranean Fever. The domain is encoded in 23 human proteins and at least 31 mouse genes.

AttributesValues
rdf:type
rdfs:label
  • Pyrin domain (en)
rdfs:comment
  • A pyrin domain (PYD, also known as PAAD/DAPIN) is a protein domain and a subclass of protein motif known as the death fold, the 4th and most recently discovered member of the death domain superfamily (DDF). It was originally discovered in the pyrin protein, or marenostrin, encoded by MEFV. The mutation of the MEFV gene is the cause of the disease known as Familial Mediterranean Fever. The domain is encoded in 23 human proteins and at least 31 mouse genes. (en)
name
  • PAAD/DAPIN/Pyrin domain (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/2KM6NLRP7NMR.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/AIM2sidetopdown.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1pn5_EBI.jpg
dcterms:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
sameAs
dbp:wikiPageUsesTemplate
thumbnail
PROSITE
  • PS50824 (en)
SCOP
InterPro
  • IPR004020 (en)
Pfam
  • PF02758 (en)
Pfam clan
  • CL0041 (en)
symbol
  • PAAD_DAPIN (en)
has abstract
  • A pyrin domain (PYD, also known as PAAD/DAPIN) is a protein domain and a subclass of protein motif known as the death fold, the 4th and most recently discovered member of the death domain superfamily (DDF). It was originally discovered in the pyrin protein, or marenostrin, encoded by MEFV. The mutation of the MEFV gene is the cause of the disease known as Familial Mediterranean Fever. The domain is encoded in 23 human proteins and at least 31 mouse genes. Proteins containing a pyrin domain are frequently involved in programmed cell death processes including pyroptosis and apoptosis. Proteins that possess a pyrin domain interact with the pyrin domains in other proteins to form of multi-protein complexes called inflammasomes and to trigger downstream immune responses. (en)
CDD
  • cd08305 (en)
PDB
  • , , (en)
gold:hypernym
prov:wasDerivedFrom
page length (characters) of wiki page
Symbol
  • PAAD_DAPIN
foaf:isPrimaryTopicOf
is Link from a Wikipage to another Wikipage of
Faceted Search & Find service v1.17_git139 as of Feb 29 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 08.03.3330 as of Mar 19 2024, on Linux (x86_64-generic-linux-glibc212), Single-Server Edition (61 GB total memory, 39 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software