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Johannes Heinrich Matthaei (born 4 May 1929) is a German biochemist. He is best known for his unique contribution to solving the genetic code on 15 May 1961. Whilst a post-doctoral visitor in the laboratory of Marshall Warren Nirenberg at the NIH in Bethesda, Maryland, he discovered that a synthetic RNA polynucleotide, composed of a repeating uridylic acid residue, coded for a polypeptide chain encoding just one kind of amino acid, phenylalanine. In scientific terms, he discovered that polyU codes for polyphenylalanine and hence the coding unit for this amino acid is composed of a series of Us or, as we now know the genetic code is read in triplets, the codon for phenylalanine is UUU. This single experiment opened the way to the solution of the genetic code. It was for this and later work

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  • Heinrich Matthaei (de)
  • J. Heinrich Matthaei (en)
  • Heinrich Matthaei (fr)
  • J. Heinrich Matthaei (pt)
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  • Johannes Heinrich Matthaei (* 4. Mai 1929 in Bonn) ist ein deutscher Biochemiker und ehemaliger Direktor der Abteilung Molekulare Genetik am Göttinger Max-Planck-Institut für experimentelle Medizin und Professor für Biochemie und Neurobiologie in Göttingen. Ihm und Marshall Nirenberg gelang 1961 der erste Durchbruch bei der Entzifferung des genetischen Codes, wofür Nirenberg den Nobelpreis erhielt. (de)
  • Johann Heinrich Matthaei est un biochimiste allemand né le 4 mai 1929 à Bonn, célèbre pour l'établissement du code génétique avec Marshall Nirenberg. Il habite actuellement à Göttingen. Il est membre de la Société Max-Planck de Göttingen après celle de Tübingen. (fr)
  • Johannes Heinrich Matthaei (born 4 May 1929) is a German biochemist. He is best known for his unique contribution to solving the genetic code on 15 May 1961. Whilst a post-doctoral visitor in the laboratory of Marshall Warren Nirenberg at the NIH in Bethesda, Maryland, he discovered that a synthetic RNA polynucleotide, composed of a repeating uridylic acid residue, coded for a polypeptide chain encoding just one kind of amino acid, phenylalanine. In scientific terms, he discovered that polyU codes for polyphenylalanine and hence the coding unit for this amino acid is composed of a series of Us or, as we now know the genetic code is read in triplets, the codon for phenylalanine is UUU. This single experiment opened the way to the solution of the genetic code. It was for this and later work (en)
  • J. Heinrich Matthaei (nascido a 4 de maio de 1929) é um bioquímico alemão, mais conhecido pela sua contribuição para a resolução do código genético em 15 de maio de 1961. Enquanto pós-doutorado visitante no laboratório de Marshall Warren Nirenberg no NIH em Bethesda, Maryland, descobriu que um polinucleotídeo de RNA sintético, composto por um resíduo de ácido uridílico repetitivo, codificava uma cadeia de polipeptídeos contendo apenas um tipo de aminoácido, fenilalanina. Em termos científicos, descobriu que os códigos poliU da polifenilalanina e, portanto, a unidade de codificação desse aminoácido era composta por uma série de Us ou, como sabemos agora que o código genético é lido em conjuntos de três, o codão da fenilalanina é UUU. Essa experiência abriu o caminho para a solução do código (pt)
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  • Johannes Heinrich Matthaei (en)
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  • Johannes Heinrich Matthaei (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/J._Heinreich_Matthaei_and_Marshall_Nirenberg_(29819142523)_(cropped).jpg
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  • National Institutes of Health (en)
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  • Max-Planck-Institut für experimentelle Medizin (en)
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