About: Group I catalytic intron     Goto   Sponge   NotDistinct   Permalink

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Group I introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of nine paired regions (P1-P9). These fold to essentially two domains – the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices). The secondary structure mark-up for this family represents only this conserved core. Group I introns often have long open reading frames inserted in loop regions.

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rdfs:label
  • Group I catalytic intron (en)
rdfs:comment
  • Group I introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of nine paired regions (P1-P9). These fold to essentially two domains – the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices). The secondary structure mark-up for this family represents only this conserved core. Group I introns often have long open reading frames inserted in loop regions. (en)
name
  • Group I catalytic intron (en)
  • Group I intron (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/GI_catalysis.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1grz_EBI.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1x8w_EBI.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1y0q_EBI.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/RF00028.jpg
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Tax domain
  • Eukaryota; Bacteria; Viruses (en)
dbp:wikiPageUsesTemplate
thumbnail
caption
  • Predicted secondary structure and sequence conservation of Group I catalytic intron (en)
id
  • RF00028 (en)
symbol
  • Intron_gpI (en)
has abstract
  • Group I introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of nine paired regions (P1-P9). These fold to essentially two domains – the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices). The secondary structure mark-up for this family represents only this conserved core. Group I introns often have long open reading frames inserted in loop regions. (en)
Rfam
  • RF00028 (en)
RNA type
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