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Gertrude "Trudy" Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, who shared the 1988 Nobel Prize in Physiology or Medicine with George H. Hitchings and Sir James Black for their use of innovative methods of rational drug design for the development of new drugs. This new method focused on understanding the target of the drug rather than simply using trial-and-error. Her work led to the creation of the anti-retroviral drug AZT, which was the first drug widely used against AIDS. Her well known works also include the development of the first immunosuppressive drug, azathioprine, used to fight rejection in organ transplants, and the first successful antiviral drug, acyclovir (ACV), used in the treatment of herpes infection.

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rdf:type
rdfs:label
  • جرترود إليون (ar)
  • Gertrude Belle Elion (ca)
  • Gertrude Belle Elionová (cs)
  • Gertrude Belle Elion (de)
  • Γκέρτρουντ Μπελ Έλιον (el)
  • Gertrude B. Elion (eo)
  • Gertrude Belle Elion (eu)
  • Gertrude Belle Elion (es)
  • Gertrude Elion (ga)
  • Gertrude Elion (in)
  • Gertrude B. Elion (en)
  • Gertrude Elion (fr)
  • Gertrude B. Elion (it)
  • 거트루드 B. 엘리언 (ko)
  • ガートルード・エリオン (ja)
  • Gertrude Elion (nl)
  • Gertrude Elion (pl)
  • Gertrude Elion (pt)
  • Элайон, Гертруда (ru)
  • Gertrude B. Elion (sv)
  • 格特魯德·B·埃利恩 (zh)
  • Гертруда Белл Елайон (uk)
rdfs:comment
  • Gertrude Belle Elion (Nova York, 23 de gener de 1918 - Chapel Hill, Carolina del Nord, 21 de febrer de 1999) fou una farmacòloga, bioquímica i professora universitària nord-americana guardonada amb el Premi Nobel de Medicina o Fisiologia l'any 1988 que va compartir amb George H. Hitchings i Sir James W. Black. Treballant sola, així com amb Hitchings i Black, Elion va desenvolupar una multitud de nous fàrmacs, l'ús de mètodes d'investigació innovadors que després ocasionarien al desenvolupament del fàrmac AZT contra la SIDA. (ca)
  • جرترود إليون (بالإنجليزية: Gertrude B. Elion)‏ (و. 1918 – 1999 م) هي أحيائية، وكيميائية، وعالمة كيمياء حيوية، وعالمة صيدلية، وصيدلانية، وطبيبة، وبروفيسورة أمريكية، ولدت في نيويورك، وكانت عضوةً في الجمعية الملكية (منذ 1994)، والأكاديمية الوطنية للعلوم (منذ 1989)، والأكاديمية الوطنية للطب، والأكاديمية الأمريكية للفنون والعلوم، والجمعية الأميركية لتقدم العلوم، توفيت في تشابل هيل، كارولاينا الشمالية، عن عمر يناهز 81 عاماً. (ar)
  • Gertrude Belle Elion (* 23. Januar 1918 in New York; † 21. Februar 1999 in Chapel Hill, North Carolina) war eine US-amerikanische Biochemikerin, Pharmakologin und Nobelpreisträgerin. Sie entdeckte wichtige Prinzipien der Arzneimitteltherapie. (de)
  • Gertrude "Trudy" Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, who shared the 1988 Nobel Prize in Physiology or Medicine with George H. Hitchings and Sir James Black for their use of innovative methods of rational drug design for the development of new drugs. This new method focused on understanding the target of the drug rather than simply using trial-and-error. Her work led to the creation of the anti-retroviral drug AZT, which was the first drug widely used against AIDS. Her well known works also include the development of the first immunosuppressive drug, azathioprine, used to fight rejection in organ transplants, and the first successful antiviral drug, acyclovir (ACV), used in the treatment of herpes infection. (en)
  • Gertrude Belle Elion (Nueva York, 23 de enero de 1918-Chapel Hill, Carolina del Norte, 21 de febrero de 1999) fue una bioquímica y farmacóloga estadounidense, que recibió en 1988 el Premio Nobel de Fisiología y Medicina por sus «descubrimientos de los principios clave sobre el desarrollo y el tratamiento de medicamentos».​ Descubrió tratamientos para la leucemia, la malaria e infecciones urinarias. (es)
  • Gertrude Belle Elion (New York, 1918ko urtarrilaren 23a - Chapel Hill, Ipar Carolina, 1999ko otsailaren 21) estatubatuar biokimikari eta farmakologoa izan zen, 1988an Medikuntzako Nobel Saria jaso zuena, George H. Hitchings eta batera. Bai bakarrik, bai Hitchingsekin elkarlanean, sendagai asko garatu zituen, hala nola, , lehenbiziko immunosupresorea, organoen transplanteetan erabilia, eta aziklobirra, lehenbiziko antibirala, herpesa tratatzeko baliatzen dena. Haren lanari esker sortu ahal izan zen HIESa tratatzeko lehen antirretrobirala, zidovudina edo AZT. (eu)
  • Bithcheimicí a rugadh i gCathair Nua-Eabhrac ab ea Gertrude Belle Elion (23 Eanáir 1918 – 21 Feabhra 1999). Chomhoibrigh sí le George Hitchins do chomhlacht Burroughs Wellcome i bhforbairt drugaí iomadúla chun an fhreagairt imdhíonach a rialú in ionchlannú, agus sintéis DNA a mhoilliú le hailse a smachtú is galair eile—leoicéime, maláire, gúta, clocha duáin, is heirpéas ina measc — a chloí. Roinn an bheirt Duais Nobel na Fiseolaíochta nó an Leighis le James Black i 1988 as an saothar sin. D'aistrigh sí go Research , in North Carolina, agus ba ansin a fuair sí bás sa bhliaiin 1999. (ga)
  • 거트루드 벨 엘리언(Gertrude Belle Elion, 1918년 1월 23일 ~ 1999년 2월 21일)은 미국의 생화학자이자 약학자로, 조지 H. 히칭스, 제임스 블랙 경과 함께 1988년 노벨 생리학·의학상을 받았다. 히칭스와 블랙과 함께뿐만 아니라 홀로도 연구했던 엘리언은 후에 후천면역결핍증후군에 쓰이는 약 AZT의 개발을 이끌어 낼 혁신적인 연구 방법을 이용해 다수의 신약을 개발하였다. 그는 장기 이식에 사용하는 최초의 면역억제제 아자티오프린을 개발하였다. (ko)
  • Gertrude Belle Elion (New York, 23 januari 1918 – Chapel Hill (North Carolina), 21 februari 1999) was een Amerikaanse farmacologe en bekend van haar onderzoek naar geneesmiddelen. In 1988 won ze de Nobelprijs voor Fysiologie of Geneeskunde, samen met George H. Hitchings en James W. Black. (nl)
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