About: Gene expression profiling

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In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.

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rdf:type	company
rdfs:label	تنميط التعبير الجيني (ar) Genexpressionsanalyse (de) Perfil de expresión génica (es) Gene expression profiling (en) Gene expression profiling (it) Количественный анализ экспрессии генов (ru) 基因表达谱 (zh)
rdfs:comment	Die Genexpressionsanalyse ist eine Untersuchung der Umsetzung der genetischen Information (Genexpression) mit molekularbiologischen und biochemischen Methoden. Sie kann sowohl für einzelne Transkripte als auch für das ganze Transkriptom angewendet werden und ermöglicht qualitative und quantitative Aussagen über die Aktivität der Gene. Während im ersten Fall nur die Sequenzinformation des zu untersuchenden Transkripts bekannt sein muss, wird für die Transkriptom-Analyse die gesamte Sequenzinformation des Transkriptoms gebraucht. (de) Количественный анализ экспрессии генов — анализ транскриптома, измерение транскрипционной активности гена с помощью определения количества его продукта, матричной РНК (мРНК), универсальной для большей части генов. При этом конечным продуктом экспрессии генов как правило являются белки, а не мРНК. (ru) 基因表达谱是一种在分子生物学领域，借助cDNA、（EST）或来测定细胞基因表达情况（包括特定基因是否表达、、不同组织、不同发育阶段以及不同生理状态下的表达差异）的方法。通过一次性测定大量基因构建起细胞功能的总体态势图，可以从图谱中区分出正在分裂的细胞，以及细胞对于特征性治疗的反应。基因表达谱还有助于了解疾病的发病机制、药物的生理反应和治疗效果。 (zh) في مجال البيولوجيا الجزيئية، يعد تنميط التعبير الجيني هو قياس نشاط (التعبير) لآلاف الجينات في وقت واحد، لتكوين صورة عامة للوظيفة الخلوية. على سبيل المثال يمكن لهذه الملامح التمييز بين الخلايا التي تنقسم بنشاط، أو إظهار كيفية تفاعل الخلايا مع علاج معين. العديد من التجارب من هذا النوع تقيس الجينوم بأكمله في وقت واحد، أي كل جين موجود في خلية معينة. (ar) In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell. (en) En el campo de la biología molecular, el perfil de expresión génica es la medida de la actividad (de la expresión génica) de miles de genes simultáneamente, para crear una imagen global de la función celular. Estos perfiles pueden, por ejemplo, distinguir entre las células que se están dividiendo activamente, o mostrar cómo las células reaccionan a un tratamiento en particular. Muchos experimentos de este tipo analizan un genoma completo simultáneamente, es decir, cada gen presente en una célula en particular. (es) Nel campo della biologia molecolare, gene expression profiling (tradotto come analisi di espressione genica) è la misura dell'attività (l'espressione) di migliaia di geni alla volta, per creare una immagine globale della funzione cellulare. Questi profili possono, per esempio, distinguere tra cellule che sono in proliferazione, o mostrare come le cellule reagiscono ad un particolare trattamento. Molti esperimenti di questo tipo misurano un intero genoma simultaneamente. (it)
foaf:depiction
dcterms:subject	Molecular genetics Genetics techniques Microarrays
Wikipage page ID	4007073 (xsd:integer)
Wikipage revision ID	1060774734 (xsd:integer)
Link from a Wikipage to another Wikipage	List of bioinformatics companies Rank product Bioconductor Cytochrome P450 DNA microarray Proteomics MRNA Molecular genetics Comparative Toxicogenomics Database Gene expression Gene expression profiling in cancer Gene nomenclature Gene signature Genome Outlier Gene Ontology Gene ontology Monte Carlo methods Multiple comparisons Cross-validation (statistics) Liver Machine learning P-value Microarray analysis techniques Microarray databases RNA-Seq ANOVA Alternative splicing Normal distribution Cellular differentiation False discovery rate KEGG Transcription factor Statistical power Hypergeometric distribution Hypothesis Genetics techniques Microarrays dbr:Cholesterol Alcohol dehydrogenase Biomarker Hierarchical clustering Bonferroni correction Bootstrapping (statistics) Omnibus test Skin Western blot Molecular biology Spatiotemporal gene expression Transcriptomics technologies Posttranslational modification Base pairing Statistical tests Transmembrane receptor Genome sequencing Transcriptomics Gene Set Enrichment Analysis Joint distribution Quantitative PCR Markov clustering Rate determining step Bioinformatician Homeostatic response K-means Kolmogorov Smirnov Splice variant analysis
Link from a Wikipage to an external page	https://doi.org/10.1016/B978-0-12-809633-8.20163-5 https://www.sciencedirect.com/science/referenceworks/9780128096338
sameAs	Gene expression profiling Gene expression profiling Gene expression profiling Gene expression profiling Gene expression profiling Gene expression profiling Gene expression profiling Gene expression profiling

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