Edward Sullivan Murphy PC(NI) KC (3 February 1880 – 3 December 1945) was an Irish barrister, judge and politician. He was brother-in-law to the first Lord Chief Justice of Northern Ireland, Sir Denis Henry, Bt. (they both married daughters of Lord Justice Hugh Holmes). He was the fourth son of James Murphy (1823-1901), judge of the High Court of Justice in Ireland, and Mary Keogh, daughter of William Keogh, judge of the Court of Common Pleas (Ireland) and Kate Rooney. His first wife Alice Holmes died in 1942; he remarried Mary Craig Buchanan.