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The endosomal sorting complexes required for transport (ESCRT) machinery is made up of cytosolic protein complexes, known as ESCRT-0, ESCRT-I, ESCRT-II, and ESCRT-III. Together with a number of accessory proteins, these ESCRT complexes enable a unique mode of membrane remodeling that results in membranes bending/budding away from the cytoplasm. These ESCRT components have been isolated and studied in a number of organisms including yeast and humans. A eukaryotic signature protein, the machinery is found in all eukaryotes and some archaea.

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  • ESCRT (cs)
  • ESCRT (en)
  • ESCRT (in)
  • ESCRT (ja)
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  • ESCRT je označení pro skupinu proteinů, které regulují vchlipování váčků (ILVs) dovnitř endozomů. Dochází tak ke vzniku tzv. multivezikulárních tělísek. Také se však účastní cytokineze a jsou využívány i virem HIV k pučení z buněk. ESCRT proteiny vytváří u savců čtyři komplexy, ESCRT-0, ESCRT-I, ESCRT-II a ESCRT-III. Každý má v procesu vchlipování váčků do endozomů jinou úlohu. (cs)
  • The endosomal sorting complexes required for transport (ESCRT) machinery is made up of cytosolic protein complexes, known as ESCRT-0, ESCRT-I, ESCRT-II, and ESCRT-III. Together with a number of accessory proteins, these ESCRT complexes enable a unique mode of membrane remodeling that results in membranes bending/budding away from the cytoplasm. These ESCRT components have been isolated and studied in a number of organisms including yeast and humans. A eukaryotic signature protein, the machinery is found in all eukaryotes and some archaea. (en)
  • Mesin kompleks penyortiran endosom yang diperlukan untuk transportasi (endosomal sorting complexes required for transport, ESCRT) terdiri dari kompleks protein sitosol, yang dikenal sebagai ESCRT-0, ESCRT-I, ESCRT-II, dan ESCRT-III. Bersama dengan sejumlah protein aksesori, kompleks ESCRT ini memungkinkan cara unik dari renovasi (remodeling) membran membentuk membran menekuk atau bertunas menjauh dari sitoplasma. Komponen ESCRT ini telah diisolasi dan dipelajari pada sejumlah organisme termasuk ragi dan manusia. Mesin ini ditemukan di semua eukariota dan beberapa arkea. (in)
  • ESCRT(endosomal sorting complexes required for transport)は細胞質のタンパク質複合体で、ESCRT-0、ESCRT-I、ESCRT-II、ESCRT-IIIという種類が存在する。これらのESCRT複合体は、他の補助タンパク質とともに独特な形式で細胞膜のリモデリングを行い、膜を屈曲させたり切り離したりする。酵母やヒトを含む多くの生物で、ESCRTの構成要素の単離と研究が行われている。 (ja)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/ESCRT_Machinery-Corrected.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/ESCRT_Mediated_Membrane_Abscission.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/ESCRT_Recruitment_During_MVB_Biogenesis.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Hiv-i.jpg
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