Cheryl H. Arrowsmith is a Canadian structural biologist and is the Chief Scientist at the Toronto laboratory of the Structural Genomics Consortium. Her contributions to protein structural biology includes the use of NMR and X-ray crystallography to pursue structures of proteins on a proteome wide scale. She received her Ph.D. in chemistry at the University of Toronto in 1987 and post-doctoral training at Stanford University working with . One of her areas of interest is the tumour suppressor p53 and related proteins.