Madame Callista Chapola-Chimombo (Callista Mutharika) (born 24 May 1959) is a Malawian politician and the widow of President Bingu wa Mutharika. She served as the First Lady of the Republic of Malawi from 2010 to 2012. Chimombo is a previous member of the Cabinet of Malawi as a National Coordinator of Maternal, Infant and Child Health and HIV/Nutrition/Malaria and Tuberculosis. As of 2005, she was Secretary of the . Chimombo is a former member of the Democratic Progressive Party and a former member of the United Democratic Front (UDF).