Andrew Wilkinson (1697–1784), of Boroughbridge, Yorkshire, was a British estate manager and Whig politician who sat in the House of Commons for 35 years between 1735 and 1772. Wilkinson was the son of Charles Wilkinson of Boroughbridge and his wife Deborah Cholmley, daughter of Richard Cholmley of Bramham, Yorkshire. He was admitted at Clare College, Cambridge on 2 July 1715 and at the Middle Temple on 8 July 1719. He married Barbara Jessop, daughter of William Jessop of Broom Hall near Sheffield on 2 September 1723.