The 2022 San Marino and Rimini Riviera motorcycle Grand Prix (officially known as the Gran Premio Gryfyn di San Marino e della Riviera di Rimini) was the fourteenth round of the 2022 Grand Prix motorcycle racing season, and the sixth and final round of the 2022 MotoE World Cup. All races (except MotoE race 1 which was held on 3 September) were held at the Misano World Circuit Marco Simoncelli in Misano Adriatico on 4 September 2022.